John M. Greally

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Dr. John Greally is a Professor in the Departments of Genetics (Division of Computational Genetics), Pediatrics (Division of Genetics) and Medicine (Division of Hematology) at the Albert Einstein College of Medicine, where he has been on faculty since 2001.  A native of Ireland, Dr. Greally received his honours degree in Medicine from the National University of Ireland in Galway in 1988, subsequently moving to the Children’s Hospital of Pittsburgh for Pediatrics residency and Yale University in 1993 for subspecialty training in Clinical Genetics.  Since his clinical training, he focused on basic science research, receiving his PhD degree in 1999 from NUIG.

Dr. Greally’s research is in the area of epigenomic regulation of the genome, and its dysregulation in disease.  Dr. Greally is the founding director of the Einstein Center for Epigenomics, where the development of computational resources to manage and analyse complex data sets from massively-parallel sequencing has been a priority from the establishment of the Center in 2008.  He serves on the editorial boards of the journals PLoS Genetics, Genomics and Epigenetics and Chromatin.  He is also involved as a member of the Scientific and Clinical Steering Committee of the New York Genome Center, and was recently appointed to Údarás na hOllscoile, the governing body of the National University of Ireland in Galway.

His research includes studies of the epigenetic regulation of stem cell differentiation and transcription-targeted cytosine methylation, and epigenetic abnormalities in human diseases such as osteosarcoma, type II diabetes mellitus, hepatitis C virus infection and allergies.  He also performs clinical duties at the Children’s Hospital at Montefiore as a Clinical Genomicist, seeing patients who have been tested with new genome-wide technologies.

 

About the LABEX:

« The LABEX DEEP initiative addresses the critical issue driving my own research, how combinations of epigenetic events can be causally associated with phenotype, a complex issue that will require the innovation and expert insights of this project. »

 

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